วันศุกร์ที่ 23 สิงหาคม พ.ศ. 2556

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Introduction
Schisandrin B, an extremely important component of GlissandrinTM, can safeguard against solar irradiation-induced oxidative injury in skin tissue and skin cells, according to recent research findings from the laboratory of Dr. Robert Ko in the Hong Kong University of Science and Technology.
As the greatest organ within the body system, your skin may serve as an efficient barrier to protect against various external threats. This includes contact with harmful solar irradiation – particularly UV and infrared rays – which research has revealed becoming a major reason behind aging of the skin. Solar irradiation-induced reactive oxygen species (ROS) generation is in charge of photo-aging, warning signs of such as wrinkles, coarse skin texture, and reduced skin resilience. Although human skin tissue possesses non-enzymatic and enzymatic antioxidant defense systems to handle the elevated oxidative stress caused by solar light radiation, long-term exposure or over-experience of solar light can overwhelm the antioxidant system.
But let's say there was clearly a means to enhance skin’s natural antioxidant defenses to stop photo-aging entirely? Schisandrin B (Sch B) is able to do just that, ushering in the new era in UV protective skincare.
Schisandrin B is derived in the Schisandra fruit, an herb frequently used in Traditional Chinese Medicine (TCM). This naturally sourced herbal ingredient has been discovered to make tissue non-specific protection against oxidative injury by enhancing cellular and mitochondrial glutathione antioxidant status inside the heart, liver, kidney, and brain.
Recent studies led by Dr. Robert Ko in the Hong Kong University of Science and Technology have demostrated the promise of Schisandrin B:

• Schisandrin B stimulated both reduced-glutathione and vitamin E levels. These two non-enzymatic antioxidants can remove excess ROS during oxidative stress in a very synergistic manner.

• Schisandrin B elevated various enzymes involved inside the enzymatic antioxidant defense system, demonstrating that non-enzymatic and enzymatic antioxidant components come together to safeguard against solar irradiation-induced oxidative injury in skin tissue.

• Schisandrin B suppressed the solar irradiation-induced increases in elastases-type protease activity and matrix-metalloproteinases-1 (MMP-1) expression in skin cells. The degradation of the extracellular matrix (EM) in skin tissue because of solar irradiation is of prime concern in skincare. This is one of the major biological events leading to photo-aging and is also mediated by protein-degrading enzymes like elastases-type protease and MMP-1.
Schisandrin B is an essential component of Glissandrin™, a potent anti-aging skincare ingredient that may be the subject of over 100 research papers. In-vivo and in-vitro research has proven the ability of Glissandrin to reverse mitochondrial decay, the best reason behind aging, also to simultaneously boost the cell’s natural power to fight oxidative damage.
Other studies have demostrated the ability of Schisandrin B to suppress collagenase, an enzyme responsible for the depletion of collagen in skin cells. Research has already been conducted on the compound’s anti-cancer properties, particularly within the skin.
Conclusion
Given that both spectra of solar light – UV and infrared radiation – are major causes of aging, Schisandrin B’s capability to enhance skin’s antioxidant defenses against harmful solar irradiation, thereby supplying the prospect of preventing skin photo-aging, is instigating a whole new era in skincare.
For more information
More information on Schisandrin B, mitochondrial decay, and theories of aging are available at these independent websites:

• National Institutes of Health (

• PubMed (

• Natural Standard (
This article was contributed by Glissandra Skincare.
About Glissandra™
Glissandra Skincare Inc. is committed to providing effective anti-aging skincare through its holistic way of skin health. Glissandra merchandise is available through its dedicated team of independent distributors, using multilevel marketing (also referred to as multi-level marketing, MLM, or direct sales). Glissandra’s pay plan offers one with the most generous payouts within the industry.
Glissandra’s comprehensive skincare method is the consequence of almost twenty years of research and development on the Hong Kong University of Science and Technology, led by Professor Robert Ko. Over 100 research papers happen to be published on Glissandra’s key proprietary ingredient, Glissandrin™, a suite of natural compounds extracted in the Schisandra berry. In-vivo and in-vitro research has proven the ability of Glissandrin to cope with mitochondrial decay, the key reason for aging, and also to improve the cell’s natural power to fight oxidative damage.



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