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Melasma is a kind of skin disorder observed in men especially women. It is quite commonly affecting expectant women and it is sometimes called the “mask of pregnancy”. Though it can impact anyone, young women with brownish skin color are in greatest risk. Melasma is usually from the female hormones estrogen and progesterone. It is especially common in expecting mothers, women who take birth control pills (oral contraceptives) and ladies taking hormone replacement therapy (HRT) during menopause. It can also be prevalent that face men and some women of Native American descent (on the forearms) and in men and some women of German/Russian and Jewish descent (for the face). The the signs of melasma are dark, irregular well demarcated hyperpigmented macules to patches commonly found around the upper cheek, nose, lips, upper lip, and forehead. These patches often develop gradually with time. Melasma won't cause some other symptoms at night cosmetic discoloration. An estimated six million women are living inside the U.S. with melasma and 45-50 million women worldwide deal with melasma; over 90% of most cases are women. Prevention is primarily directed at facial sun protection and sun avoidance.
Treatments to hasten the fading with the discolored patches include: Azelaic acid (20%) Skinoren, shown to limit the activity of melanocytes. Skinoren normalizes the disturbed keratinization processes inside the follicles of oil glands and decreases the content of free fatty acids inside the lipids from the skin and reduces its fat content. Skinoren exhibits antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis. Anti-inflammatory effect can also be because of decline in metabolism of neutrophils and decreased production of molecular oxygen species. Skinoren features a dose-dependent and time the overwhelming impact for the growth and viability of abnormal melanocytes.
Before use Skinoren, the skin is thoroughly washed with pure water, cream should be used twice per day, about the affected skin, gently rubbing into skin. Individual course of treatment: a couple of months - for your treatment of acne, a few months - for melasma. Clinical improvement occurs after an average of 2-4 weeks. If necessary, repeat the course - the break 1-2 months. During the treatment methods are required to protect the skin from your entire spectrum of solar radiation. In case of severe skin irritation inside the first week of treatment, apply one time per day; possible short-term removal in the drug, then the resumption after the disappearance of the signs of irritation in the recommended dose.
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